‘People Are Dying’: Battling Coronavirus Inside a N.Y.C. Hospital | NYT News

‘People Are Dying’: Battling Coronavirus Inside a N.Y.C. Hospital | NYT News

An emergency room doctor in Elmhurst, Queens, gives a rare look inside a hospital at the center of the coronavirus pandemic. “We don’t have the tools that we need.”

Predictive Pattern Classification Can Distinguish Gender Identity Subtypes from Behavior and Brain Imaging

Predictive Pattern Classification Can Distinguish Gender Identity Subtypes from Behavior and Brain Imaging

Abstract
The exact neurobiological underpinnings of gender identity (i.e., the subjective perception of oneself belonging to a certain gender) still remain unknown. Combining both resting-state functional connectivity and behavioral data, we examined gender identity in cisgender and transgender persons using a data-driven machine learning strategy. Intrinsic functional connectivity and questionnaire data were obtained from cisgender (men/women) and transgender (trans men/trans women) individuals. Machine learning algorithms reliably detected gender identity with high prediction accuracy in each of the four groups based on connectivity signatures alone. The four normative gender groups were classified with accuracies ranging from 48% to 62% (exceeding chance level at 25%). These connectivity-based classification accuracies exceeded those obtained from a widely established behavioral instrument for gender identity. Using canonical correlation analyses, functional brain measurements and questionnaire data were then integrated to delineate nine canonical vectors (i.e., brain-gender axes), providing a multilevel window into the conventional sex dichotomy. Our dimensional gender perspective captures four distinguishable brain phenotypes for gender identity, advocating a biologically grounded reconceptualization of gender dimorphism.We hope to pave the way towards objective, data-driven diagnostic markers for gender identity and transgender, taking into account neurobiological and behavioral differences in an integrative modeling approach.

Groundbreaking study reveals how transgender hormone therapy affects medical test results

Groundbreaking study reveals how transgender hormone therapy affects medical test results

Groundbreaking research presented at the 71st AACC Annual Scientific Meeting & Clinical Lab Expo has revealed how transgender hormone therapy affects the results of common laboratory tests in the long term. This first-of-its-kind study could enable the development of transgender-specific reference intervals, which are crucial to ensuring that transgender patients get accurate diagnoses and equitable healthcare.

Hormone therapy helps strengthen brain connections in transgender women

Hormone therapy helps strengthen brain connections in transgender women:

In transgender women who have had their testes removed as part of the gender-affirming process, a form of estrogen called estradiol strengthens connections between areas of the brain involved in fine motor skills, learning, emotions and sensory perception, according a study to be presented Monday at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La. These findings reflect changes on the brain that might have implications, for instance, for treating hot flashes and other symptoms in transgender women, the researchers say.

Oops

It seems I am having an allergic reaction to something, scratchy throat and swollen lips. At this point I can’t drink anything because it runs down my chin 😦

The good thing is I’m not having any trouble breathing or swallowing… at least not yet.

I have someone who is going to pick up some benadryl which I hope will help. I really don’t feel like spending the night in the ER.

One way or another I’ll be sure to post an update when I get the chance.